The World Health Organization (WHO) and Africa CDC have declared a public health emergency following a rapidly expanding outbreak of Ebola in Central and East Africa. Unlike recent epidemics, health officials confirmed that this outbreak is driven by the Bundibugyo virus, a rare strain of Ebola for which there are currently no approved vaccines or targeted treatments.
The outbreak was officially declared on May 15, 2026, in the Ituri Province of the northeastern Democratic Republic of the Congo (DRC). It has since spread to neighboring North Kivu and South Kivu provinces, and crossed the border into Uganda, with confirmed cases reaching major urban centers including Kampala and Goma.
According to the latest data from the World Health Organization and the U.S. Centers for Disease Control and Prevention (CDC), health authorities have tracked 968 suspected cases and at least 216 deaths across the region. Out of these, there are 83 laboratory-confirmed cases in the DRC and 5 in Uganda. Health agencies report that the true number of infections likely exceeds current official counts due to the remote nature of the affected zones and ongoing security challenges in the region.
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The specific virus responsible for this spike in cases alters the medical response significantly compared to prior outbreaks.
“What makes this outbreak different and significantly harder to fight is the type of virus that causes Ebola disease,” said John Johnson, the medical lead for epidemic response at Doctors Without Borders (MSF). “This is the Bundibugyo virus—not the same virus the world knows from the major West Africa epidemic that occurred between 2014 and 2016. That outbreak, and the 2018–2020 one in DRC, ultimately drove major scientific advances: Vaccines and treatments now exist for that specific virus, known as ‘Ebola virus’ (formally called the ‘Zaire virus’). But for the Bundibugyo virus—which also causes Ebola disease—no vaccine or treatment has been approved so far.”
Patients infected with the strain present with severe symptoms, including high fever, body pain, extreme weakness, vomiting, and in some instances, internal and external bleeding. Local health systems are under immense strain, and at least four healthcare workers have died after contracting the virus in clinical settings.
The geographic spread is compounded by high population mobility, local mining operations, and a complex humanitarian crisis in northeastern DRC. The Red Cross reported that three of its workers who died in mid-May are believed to have contracted the virus as early as late March while managing deceased bodies, suggesting the virus was circulating weeks before it was formally identified.
In response to the international spread, the United States, Canada, and several Latin American nations have instituted strict travel measures. The U.S. Department of Homeland Security and the CDC enacted entry restrictions, rerouting all arriving citizens and residents who visited the DRC, Uganda, or South Sudan within the previous 21 days through Washington Dulles International Airport for health screenings. Non-U.S. citizens who have visited those nations are currently restricted from entering the country.
The CDC noted that the overall risk to the general public outside of the immediate East and Central African region remains low, as no cases have been confirmed in the United States or Europe. Emergency scientific consultations are currently underway in Geneva to expedite research and development into potential medical countermeasures specifically targeting the Bundibugyo strain.
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